In addition to the diagnosis of fractures, X-rays now allow scientists to take close-up shots of the virus, and the virus image is not contaminated at all. This achievement will soon help doctors develop new antiviral drugs.

By concentrating powerful X-rays on a herpes virus, without any staining, scientists at the University of California, Los Angeles took the first high-definition image of the virus. This technology is the so-called X-ray diffraction microscope, which can promote the development of new drugs for the treatment of different diseases. A similar technique is X-ray crystallization, which has been used for many years to determine the structure of many important proteins, including the double helix structure of DNA. John Mio of the University of California, Los Angeles, responsible for this research, said: "This is a very important technology, and many Nobel Prizes have been won for this technology."

The disadvantage of X-ray crystallization is that it can only be applied to crystals, and DNA and some proteins can become crystals after sufficient repetition, but other proteins, especially those found in cell membranes, cannot form crystals because they are not soft and Change, of course, the entire cell can not be crystallized. Mio said: "Like human cells, no two human cells are strictly the same." Mio and his colleagues broke this limitation by using the world's most powerful X-ray machine. This X-ray machine is located in Japan's SPring-8 synchrotron.

Scientists chose the herpes virus because its relative diameter is 100-200 nanometers, and it also has great medical value. The operation process is: they put the virus into the synchrotron, and then irradiated the sample with X-rays. The camera on the opposite side can detect a slight change in the light released on the other side, and then use computer software to piece together the pictures taken by X-rays to form an overall image of the herpes virus. The Miu team created the first image of a single virus without staining, which is three orders of magnitude smaller than the images obtained by other technologies. Images of other cells and viruses are obtained by staining and slicing, and then the pictures are pieced together to form an overall image, but this process seriously destroys important life information.

The new technology can capture 22-nanometers, and scientists also said that Stanford University in Germany is developing a more powerful X-ray machine that can capture clearer images of smaller proteins and cells. These images will be a boon for drug developers, Mio said. "You can understand the function of a protein from its structure, and then we can develop a new drug that will make the protein lose its function." (Nite)

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