How to choose a suitable laboratory spray dryer

20130121133843445_Copy.jpg

Shanghai Haozhuang Instrument Co., Ltd. Haozhuang (LNB) brand small spray dryer-spray drying is a method of systematic technology applied to material drying. After the liquid material is atomized in the drying chamber, it is in contact with hot air In the process, the water vaporizes instantly to obtain a dry product. This method can directly dry the solution and emulsion into a powder or granular product, which can save the steps of evaporation and crushing, and the particles are evenly distributed.

Spray drying has the characteristics of fast heat transfer, rapid evaporation of water, instant drying time, good product quality and good dissolution performance, which can improve the dissolution rate of certain formulations. In addition, spray drying can also be used to prepare microcapsules.

"Workers want to do their best, must first sharpen their tools", according to the physical or chemical properties of different materials, as well as the size and solubility of the powder or granules required by the experiment, researchers may need to type laboratory spray Only the dryer can get the best experimental effect.

1) High sugar content (if juice, Chinese herbal medicine or natural product extract) or heat sensitive materials

Because most polysaccharide disaccharides have a relatively low melting point, the sugar melts when heated, and the polysaccharide disaccharide itself is relatively easy to absorb moisture, so the ordinary spray dryer will easily stick to the wall, not easy Get good dry powder or granules. In addition, like enzyme preparations, live bacteria, and some polymer materials that are more easily denatured at high temperatures, using ordinary spray dryers, the materials are very susceptible to inactivation or denaturation. At this time, reduce the air inlet temperature and air outlet of the spray dryer Temperature, you can get better experimental results, Shanghai Haozhuang Instrument Co., Ltd. L-6000Y laboratory spray dryer and L-6000 laboratory low temperature spray dryer can be tested at a relatively low inlet air temperature, for example, L -The inlet air temperature of 6000Y laboratory spray dryer can be set to 110 ℃. Generally, the materials with high sugar content can get better particles. The sugar content of some materials may have a lower melting point, and the L-6000 laboratory low temperature spray dryer can complete the spray dryer process at an inlet air temperature of 60-80 ° C, such as enzyme preparations, live bacteria, etc. The temperature is instantaneous and the activity is not affected at all.

2) The solvent is organic solvent or easily oxidized material

The spray drying contains organic solvent. It is difficult to dry the material. Generally, the organic solvent will be flammable and explosive. The explosion-proof closed laboratory spray dryer allows the material to circulate in the closed drying system. The whole system is filled with inert gas. (For example, nitrogen or argon), it can avoid the contact between the organic solvent gas and the outside oxygen air, ensuring safe production. Shanghai Haozhuang L-6000Y experimental organic solvent spray dryer uses a safe nitrogen (or other inert gas) closed circulation method, the entire system is fully closed, and the oxygen concentration is monitored online. Once the oxygen concentration in the system reaches 1.5% , The system will automatically shut down and alarm. It is a small spray dryer for laboratory organic solvents with good safety and easy operation. It can be used for flammable and toxic solvents through the use of nitrogen closed circulation and complete solvent recovery. It can be processed and can be easily dried. Moreover, since the boiling point of the organic solvent is low, it is possible to dry materials that are easily thermally denatured by low-temperature drying.

3) Materials that require large particles

In the course of some experiments, scientific researchers hope to obtain some samples of large particles. For example, in the catalyst industry, particles of about 100 microns are generally required to have better catalytic effects, but ordinary spray dryers can only obtain particles below 30 microns. , L-6000 laboratory spray drying granulator, can achieve the experimental purpose better. The L-6000 spray granulator can be used as a separate spray dryer to obtain particles of about 100 microns, and it can also achieve the granulation of small particle powders and can obtain large particles above 100 microns.

4) Materials with extremely poor thermal sensitivity or requiring improved solubility

Some materials can hardly be heated, the traditional freeze-drying time is very long, and the dried materials are in the form of lumps, poor fluidity, and poor solubility. Compared with the traditional freeze-drying technology, the L-6000Y laboratory spray freeze dryer has the following advantages: (1) The atomized and dispersed small droplets are immersed in low temperature to freeze quickly, which can weaken the growth of ice crystals and reduce the lipid of ice crystals. The destruction of the body to avoid drug leakage and burst release; (2) The frozen sample was dried in vacuum to form spherical particles with a microporous structure, good fluidity, and the size of the particles can be adjusted by changing the spray process. L-6000Y laboratory spray freeze dryer is suitable for low temperature drying of heat sensitive, viscous, active materials and high sugar content materials, such as Chinese herbal medicine natural product extracts, dairy products, biological preparations, enzyme preparations, fruit juice , Polymer materials, etc.

For materials that require direct access to nanomaterials, the L-6000 laboratory spray freeze dryer is also an excellent choice.

5) Conventional materials

Some laboratories are used for the preparation of conventional powders or the drying of materials. You can choose Haozhuang L series laboratory spray dryer, which is small in size, fast in speed, low in noise, easy to operate, and 20ML material can complete an experiment and dry it out. The powder has good sphericity, and the particle size is distributed too positively, especially with the spray head water cooling device and tower wall purge function, which greatly expands the application of laboratory spray dryers.

For more information about small spray dryers, please consult Shanghai Haozhuang Instrument Co., Ltd., Shanghai Haozhuang Instrument Co., Ltd. R & D, production and sales: spray dryer, spray dryer, spray dryer, small spray dryer, small spray dryer Machines, small spray dryers, experimental spray dryers and other laboratory instruments, welcome your inquiry and purchase!

Jewelry Packaging

Jewelry Packaging,Jewelry Gift Boxes,Paper Jewellery Box,Jewelry Box

Apache Industry Ltd. , https://www.apachedisplay.com