On February 8, Ms. Han, the first patient who successfully accepted 3D printed pelvic implantation in Hubei Cancer Hospital, was discharged. A month ago, the doctor completed the pelvic prosthesis replacement after removing the patient's bone tumor.

At the beginning of 2017, Ms. Han, who is 48 years old, began to feel pain in the lower right side of the waist. Sometimes she even felt that her right leg could not touch the ground and it was difficult to walk. Upon examination, she found a large osteosarcoma in her right pelvis. In May 2017, Ms. Han went to the Department of Surgery, Hubei Provincial Cancer Hospital for surgical treatment of bone soft tissue. After 4 times of chemotherapy, she saw a significant reduction in tumors. Wang Huabin, director of the hospital's bone soft tissue surgery, suggested that she surgically remove the tumor because it was said that the operation was difficult. The risk is high, Ms. Han still insists on continuing chemotherapy.

But slowly, chemotherapy drugs have not been able to control the tumor. From October to December 2017, Ms. Han’s tumor rapidly increased to more than 10 cm. The pain was more intense than at the beginning of the year. Not only could she not stand, she could not even lie flat, she could not sleep at night, and she had to eat a lot every day. Pain medication to relieve pain. Unable to stop, she finally decided to undergo surgery. I heard that I can use the 3D printing technology to "tailor-made" the pelvis. Ms. Han and her family want to give it a try.

Because of the first use of 3D printing technology in the surgical treatment of cancer patients, Wang Huabin and his team are very cautious.

Before the operation, under the guidance of Wang Huabin, 3D printing company analyzed the size of tumor lesions according to the three-dimensional CT data of the patient's pelvis and calculated the extent of tumor and bone tissue resection, and printed a pelvic model. After getting the model, Wang Huabin and the team doctor repeated the simulated surgery to further accurately assess the extent of pelvic damage and optimize the scope of resection. Subsequently, according to the final resection plan, the titanium alloy prosthesis of the pelvic defect part was precisely customized.

On January 10, the operation was officially implemented. In the hospital operating room, anesthesiology department, and interventional department, the medical staff successfully completed the right hip and hip malignant bone tumor resection, 3D printed pelvic prosthesis implantation, and right femoral head replacement after 8 hours. A series of operations such as soft tissue reconstruction, almost 90% of the right pelvis was removed during the operation.

Wang Huabin said that in the absence of 3D printing technology, patients with osteosarcoma undergo tumor resection, usually implanted artificial pelvis, usually mass-produced prosthesis of the same size, which is easy to cause prosthesis and pelvis The size of the defect is not the same, the patient will be lame after surgery, and there is obvious discomfort; and the 3D printed pelvic prosthesis implanted by Ms. Han is customized according to the shape and size of the patient's defect bone tissue, all irregular places are Can match one by one.

In addition, when the bone tissue is printed in 3D, the bionic simulation is carried out according to the trabecular structure of the trabecular bone, which can be well fused with the real bone tissue of the border, which not only improves the adhesion of the prosthesis, but also facilitates the early recovery of the patient. The postoperative recovery time for 3D printed pelvic implantation can be shortened from 3 to 6 months to 1 to 2 months compared to conventional artificial pelvic implantation.

After nearly a month of postoperative treatment and conditioning, Ms. Han's physical and mental condition has greatly improved, and the pain that has plagued her for a long time has disappeared. She plans to cooperate with the doctor for follow-up anti-cancer treatment after the Spring Festival. (People's Daily / Zhang Pei, Wang Fang, Wang Yeling)

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